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Chunk #72 — Determinants of BAC — Genetic polymorphisms in alcohol metabolizing enzymes — Other genes involved in alcohol metabolism: CYP2E1 and rare variants

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Recent advances in alcohol metabolism: from the gut to the brain.
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There are several CYP2E1 polymorphisms, and while their impact on alcohol metabolism has not been studied as much as ADH and ALDH variants, they are implicated in variability in alcohol metabolism and alcohol-induced liver injury (183).