Together, projections from PFC and ACC cortical areas terminate primarily in the rostral striatum, including the VS, caudate, and putamen. Whereas terminals are mostly located rostral to the anterior commissure, a small portion continues caudally for some distance. 14,19 The PFC and ACC are comprised of several regions that are associated with reward, motivation, and cognition. According to specific roles for mediating different aspects of these behaviors, these regions can be functionally grouped into: (i) the OFC; (ii) the dACC; (iii) the vmPFC, which includes medial OFC, the subgenual ACC, and area 10; and (iv) the dorsal PFC (dPFC).
