At baseline, about one-half (51.2%) of adolescents had tried alcohol and about one-quarter had tried cigarettes (26.6%), marijuana (24.6%) or other drugs (24.6%). Fewer youth reported past month substance use at baseline – alcohol (5.8%), cigarettes (7.8%), marijuana (9.7%), and other drugs (9.7%). Past month use rates increased over the one-year period for alcohol (8.7%), cigarettes, (11.0%), marijuana (15.0%), and other drugs (15.0%). Boys were significantly more likely to report use of marijuana, other drugs, and any drugs than were girls; girls and boys did not differ significantly in their use of alcohol and tobacco. In regards to grade, high school students were more likely to report higher rates of use for all substances; these differences were pronounced at time 1 and had diminished by time 3.