Chunk #49 — Materials and Methods — Identification of Genes That Contained Convergent Data from Two Samples: 2) “Cluster Than Converge”

Source

Genome wide association for addiction: replicated results and comparisons of two analytic approaches.

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To provide controls for the possibility that observed abuser-control differences were due to a) occult ethnic/racial allele frequency differences or b) noisy assays, we assessed the overlap between our results and SNPs that displayed the largest a) allele frequency differences between African-American vs European-American control individuals and b) the largest assay “noise”.