In GBD 2016, locations are arranged as a set of hierarchical categories: seven super-regions, 21 regions nested within the seven super-regions, and 195 countries and territories nested in the 21 regions. Additionally, we present estimates at the subnational level for five countries with a population greater than 200 million in 2016: Brazil, China, India, Indonesia, and the USA. We produced a complete set of age-specific, sex-specific, cause-specific, and location-specific estimates of risk factor exposure and attributable burden for 1990–2016 for all included risk factors.