Overall, this analysis follows the CRA methods used in GBD 2015.4 The methods described in this study provide a high-level overview of the analytical logic, focusing on areas of notable change from the methods used in GBD 2015, with details provided in appendix 1 (p 10). This study complies with the Guidelines for Accurate and Transparent Health Estimates Reporting (GATHER) statement14 (appendix 1 p 377).
