Chunk #17 — Results — 5-HTTLPR effects on BSI anxiety

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Variability in the effect of 5-HTTLPR on depression in a large European population: the role of age, symptom profile, type and intensity of life stressors.

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Using linear regression analysis, BSI anxiety increased with the increasing number of s alleles (Table 2 and Fig. 1E, Table E in S1 File), irrespective of recent negative life events. This effect was significant in the younger (≤30) subpopulation but was not present in the elder (>30) subpopulation (Table 2, Figs. B-E and B-F in S1 File). However, there was no significant 5-HTTLPRxRLE interaction on BSI-ANX (Table 2).