variation in ZEB2 may have broader neurobiological implications, beyond epilepsy. While no previous genetic association studies have provided a clear association of either ZEB2 or CTBP2 and beta EEG, mRNA expression in key brain regions for beta EEG, along with associations with potentially related traits (i.e., AUD, alcohol and cigarette use frequency, epilepsy) could provide a potential link for the association of ZEB2, CTBP2 and beta EEG. These conclusions however, are beyond the scope of the present study and must be explored in future, independent studies.
