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Chunk #43 — Methods — mC and histone profiles

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Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells.
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Figure 5c is as in Fig. 4a lower axis, but based on the mC in the CH sequence context profiled over non-CG mega-DMRs and upstream/downstream flanking regions minus the non-conversion frequency. In the upper axis the H3K9me3 histone modification ChIP-Seq reads were profiled as described for the H3K27me3 profiles in Fig. 4a.