Chunk #42 — Methods — mC and histone profiles

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Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells.

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Figure 5b is as in Fig. 4a lower axis, but based on the mC in the CH sequence context profiled over the non-CG mega-DMRs and upstream/downstream flanking regions, minus the non-conversion frequency. The final profiles were normalized to their maximum level.