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Chunk #9 — Results — Replication of ADH genes associations

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A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.
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Among ever drinkers in this pooled analysis, the minor allele carriers of rs1229984 reported consuming less alcohol than non-carriers (p = 3×10−20). rs1573496 minor allele carriers similarly were noted to consume somewhat less alcohol (p = 0.002), while rs698 minor allele carriers consumed slightly more (p = 0.05) (Table 2). Adjustment for alcohol consumption made little difference to the risk estimates for UADT cancer with all three variants (Table S4).