We additionally genotyped the five variants significantly associated with UADT cancer in 537 African American UADT cancer cases and 539 controls noting a significant association for the 12q24 variant rs4767364 (p = 0.004) (Table 3). Nevertheless, the smaller sample size and potential differences in genetic architecture between European and African American populations (both in terms of allele frequencies and LD structure) limits our ability to assess these five alleles in African-Americans.
