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Chunk #7 — Results — Heritability of PTSD

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International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.
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× 10−10Estimates are calculated using LD-score regression (LDSC) at different population prevalences after trauma exposure for the combined PGC freeze 2 samples, and separately for PGC1.5 (without the UK biobank), the UK biobank, and for men and women. Number of SNPs ranges from 1,160,174 to 1,175,791P-value is testing if h2SNP is different from zero and applies to all prevalencesPGC2 all European ancestry subjects of PGC freeze 2 (including the UK biobank), PGC1.5 European ancestry subjects in the PGC1.5 EUA (not including the UK Biobank subjects), UKB UK Biobank European subjects, h2SNP mean SNP-based heritability, 95% CI 95% confidence interval, prev prevalence