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Chunk #55 — Methods — Cell type abundance

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Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder.
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scCODA81 was used to test for relative differences in abundance of cell clusters between AUD and non-AUD groups, using an FDR cutoff of 0.05. A nonzero “final parameter” statistic for a given cell type indicates a statistically significant difference in abundance.