Chunk #56 — Methods — ATAC-seq integration, visualization

Source

Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder.

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Peaks from each of the Signac objects were merged to create a common peak set. Each of the 23 objects was then processed using the standard ATAC-seq procedure in Signac—FindTopFeatures, RunTFIDF, RunSVD—and all objects were then integrated using the IntegrateEmbeddings command.