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Chunk #10 — Materials and Methods — Statistical Analysis — Estimation of Additive Genetic Effects

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The etiology of DSM-5 alcohol use disorder: Evidence of shared and non-shared additive genetic effects.
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1; N=43,093) (Hasin and Grant, 2015) and, for craving from the National Longitudinal Alcohol Epidemiologic Survey (NLAES)(Grant et al., 2003). Craving in NLAES was defined by endorsement of at least one of two possible items: ‘Want to drink so badly that you couldn’t think of anything else’ and ‘Feel a very strong desire or urge to drink’. Prevalence was calculated for individuals in NESARC and NLAES who (1) self-reported non-Hispanic White ethnicity, (2) were aged 18–79 years, and (3) reported lifetime exposure to alcohol (see Table 2). All analyses controlled for gender, age, and the first five ancestral principal components.