A human laboratory study was conducted to determine whether rs2023239 was associated with the rewarding effects of alcohol. Fifty-six individuals had the TT genotype, 15 had the CT genotype, and 3 had the CC genotype for rs2023239. The individuals with the CC and CT genotypes were combined into 1 group to facilitate analyses. The first set of analyses tested for differences between the TT and CT groups on demographics and alcohol/ other drug use variables. There were no differences in self-reported ancestry. There was 1 individual with African American ancestry in the TT group; the CT group included 1 Latin American, 1 Asian, and 1 African American individual. Of the TT group, 50% smoked tobacco, and of the CT group, 54% smoked tobacco. There were no significant differences (P > .05) between the TT and CT groups in mean (SD) age (21.6 [3] years vs 22.4 [3] years), sex (66% vs 79% male), or mean (SD) past-month quantity of alcohol use measured using a 30-day timeline follow-back method (72 [50] vs 72 [41] standard drinks). Mean breath alcohol levels after
