1998), which are thought to influence drinking behavior. The three additional loci identified in the present study, 1p22.3 (Corbett et al., 2005; Foroud et al., 2000; Guerrini et al., 2005; Hill et al., 2004; Kuo et al., 2006; Reich et al., 1998), 9p24.1-p23 (Gelernter et al., 2008; Long et al., 1998; Prescott et al., 2006) and 22q12.3-13.1 (Bergen et al., 2003; Foroud et al., 2000; Prescott et al., 2006), have all been previously identified in linkage studies of alcohol misuse phenotypes. Thus, the findings reported in the present study provide further evidence supporting several genomic regions as harboring susceptibility loci for alcohol dependence.