Chunk #9 — Materials and methods — Statistical analysis — CIP study

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Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations.

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The chi-square test was used to compare allele, genotype and haplotype frequencies between groups of unrelated cocaine dependent individuals with and without paranoia. PHASE version 2.1 (Stephens and Scheet, 2005; Stephens et al., 2001), was also used to reconstruct haplotypes for each group.