Similar associations were observed with the C allele of rs1477196, the second most significant SNP in the OOA. In the OOA, each risk allele for rs1477196 was associated with a mean (SD) increase in BMI of 0.84 (0.25) (P <.001). The SNPs rs1861868 and rs1477196 are 17.9 kb apart in intron 1 and are in moderate LD in the OOA (D′=0.82; r2=0.36).
