The 37 smokers (including 19 women) had a mean age of 40.8 (13.2) years (range, 19-61 years) and initiated smoking at 16.5 (3.7) years of age. They smoked a mean of 16.2 (5.1) cigarettes per day, had a mean FTND score of 4.9 (1.6), and smoked for a mean of 24.3 (13.7) years. Mean withdrawal scores (11.5 [8.4]) and urge scores (43.7 [16.4]) in the abstinence state were significantly higher than in the smoking state (3.3 [3.8] and 23.9 [10.8], respectively; P = .0001). Negative affect was higher in the abstinence vs smoking states (15.4 [6.6] vs 11.4 [2.5]; P = .0001). Abstinence was associated with slower median correct response time (P = .002) and lower d prime (P = .004).
