of the sequencing data where it could be confirmed directly. SKAT analyses of the 8271 subjects showed a statistically significant association between these 11 RVs and OD in AAs (P=0.00080). Results from gene-based association tests showed that the association signal derived mostly from DISC1 (P=0.0010) and GRIN2B (P=0.00085) (Table 3). It is possible that these RVs influence protein expression and/or function, and thus contribute to OD risk in AAs.
