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Chunk #6 — Methods — GTEx eQTL Data

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Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets.
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The GTEx version 7 data set includes eQTL data from 13 brain tissues with sample sizes ranging from 154 to 80: cerebellum, caudate, cortex, nucleus accumbens, cerebellar hemisphere, frontal cortex, putamen, hippocampus, anterior cingulate cortex, hypothalamus, amygdala, spinal cord (cervical C1), and substantia nigra.7 Gene expression in these samples has been obtained using paired-end RNA-seq (Illumina TruSeq; Illumina Inc) and genotype data from whole-genome sequencing. Full-summary eQTL data for the tissues of interest were downloaded from the GTEx web portal.18