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Chunk #32 — EXISTING hiPSC MODELS OF NEUROPSYCHIATRIC DISEASE — Alzheimer’s Disease

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Genetics of Alcohol Use Disorder: A Role for Induced Pluripotent Stem Cells?
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Together, these studies highlight the utility of hiPSC-derived CNS cells for exploring genetically complex neuropsychiatric disorders. Table 1 lists recent publications utilizing hiPSCs for investigating polygenic neuropsychiatric diseases (for reviews, see (Ardhanareeswaran et al., 2017; Prytkova and Brennand, 2017; Shi et al., 2017; Soliman et al., 2017). Though some caveats and limitations exist (discussed below), the rapidly advancing field of hiPSC differentiation and associated analytical platforms is rife with potential.