Demographic and drinking characteristics were compared across groups for each phase by Generalized Estimating Equations (GEE(63)). Pearson correlations were used to examine the association of each alcohol response (net change in stimulation, sedation, and cortisol; change in like, and want more) at initial and re-examination phases. These variables were examined in GEE models testing effects of group (HD, LD), phase, and their interactions. To further investigate the source of group differences, GEE analyses compared alcohol responses by phase among the three HD AUD trajectory subgroups. If the interaction was not significant, then this term was removed to examine the main effect of group or phase. Since FH is as a potential risk factor for development of alcohol problems(64), analyses were repeated including FH as a covariate with FH coded by 2 dummy variables: FH positive vs. negative, and FH not sure vs. negative.
