Given the large number of electrophysiological observations available in the COGA Prospective study, it became possible to estimate mean rates of change of development with considerable accuracy. This enabled the identification of striking gender differences in the age-specific developmental patterns of theta band EROs, but relatively little gender modulation of spatial differences. Preliminary studies of other P3 related measures derived from the same subjects with the same methodology show similar patterns of gender differences in mean rates of change. In addition, the trajectory of correlations between the six electrophysiological variables examined in this study indicated a developmental divergence and reconvergence between auditory and visual systems. This suggests that relatively large neurophysiological systems influenced by multiple genetic factors may experience coordinated developmental patterns regulated by gender and modality specific effects. In a forthcoming study, the developmental trajectories of the associations between genetic variants (SNPs) from a number of genes associated with neurophysiological functions and the measures of the power of theta EROs are studied using the same data set and similar methodologies. Since measures of the P3 response have been found
