their transcripts was significantly correlated (Table S419) [A marker located between NKAIN1-SERINC2 and OPRD1, i.e., rs1009080 at PTPRU, has been associated with schizophrenia (p=2.5×10−6) by a recent GWAS (Ripke et al., 2011)]. These findings suggest that NKAIN1-SERINC2 may also be implicated in alcohol dependence via the neurotransmitter systems or metabolic pathways, although the actual relationships between NKAIN1-SERINC2 and those neurotransmitter systems and signaling pathways can only be delineated with analyses beyond simple pairwise correlations.
