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Chunk #29 — RESULTS — Use cases — Finding experimental tools

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TCRD and Pharos 2021: mining the human proteome for disease biology.
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A researcher has found that a Voltage-gated potassium channel, KCNS2, is expressed in the nucleus they are working on. It's role is unknown. The target details page for KCNS2 lists three approved drugs (e.g. amifampridine) which are known to block this channel. The IDG Resources show a cell line and a mouse genetic construct, which can be ordered from the IDG Consortium (UCSF, in this case). The researcher is now able to design a set of in vitro and in vivo experiments to help elucidate the role of the channel.