A researcher studying asthma searches for this top level disease term and enters the asthma disease details page. He wants to find proteins that are differentially expressed in asthma patients. Starting from the Asthma disease details page, he clicks ‘Explore Associated Targets’ to see 470 potential targets. Filtering those with data from the Expression Atlas (18), using the ‘Expression Atlas’ value from the ‘Disease Data Source’ filter, yields 78 targets, which can then be sorted by log2foldChange using the drop-down sort feature, as shown above the target list in Figure 10. He finds several with high log2foldChange, meaning the expression level changes drastically between disease and non-disease conditions, and low p-value, meaning the results are statistically significant. Also of note, for lists of associated targets, an additional column has been added to the target card, showing disease association details, such as the evidence associated with a given data source.
