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Chunk #31 — Results

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Is the gene-environment interaction paradigm relevant to genome-wide studies? The case of education and body mass index.
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yes

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even moderately significant for both groups) and only a limited number of SNPs that come close to replicating across the two groups. To further contextualize these distributions, we repeated these figures using the simulated environment described earlier; these are plotted in the bottom half of Fig. 4. As with the true environmental model, the simulated environmental model yields p values whose logarithms are negatively correlated with one another and, again, no consistent evidence for the reliability of genetic signals amid a sea of noise.