In the Hispanic cases (age range of 18–60 years, median 34, mean 35), there was a significant point-wise correlation of DNA methylation with age at the −18 CpG site (r2 = 0.19, 95% CI 0.00–0.36, P = 0.047). None of these correlations were significant after adjusting for multiple testing. Thus, although several CpG sites were found to be correlated with age with point-wise significance, there was no significance found with all 16 CpG sites combined.
