At the time of the maximum P3 amplitude (805 ms–810 ms), females showed much stronger neuronal activation than males in response to both chemosensory stimuli (Fig. 2). In females, centrally located neuronal activity was related to either odor source, whereas medial frontal activation was specifically associated with the perception of chemosensory anxiety signals. The prefrontal activation appears with a left sided dominance between 400 and 600 ms after stimulus onset and reappears between 700 and 900 ms with a medial dominance. After 900 ms the frontal activity vanishes. However, the non-specific central activation can be observed 500 ms after stimulus onset and remains with slight local changes for about 1 s (see Supplementary Material, Video S1).
