The trend in unsafe sex coincides with the HIV/AIDS epidemic. Figure 3 shows that unsafe sex experienced large increases between 1990 and 2006, by 198·8% (170·45–228·2) for men and 204·0% (170·0–236·4) for women, resulting in a higher rank in 2006, followed by declines of 43·8% (41·7–45·7) for men and 46·7% (44·1–49·0) for women since 2006 resulting in a lower rank in 2016. On the other hand, drug use follows a different trend, and increased for men by 17·6% (13·0–25·5) between 1990 and 2006 and resulted in a higher rank in 2006, and decreased 5·7% (2·2–9·0) since 2006. Despite declines, drug use rose from the 25th leading risk to the 18th leading risk for men between 1990 and 2016.
