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Chunk #20 — Discussion

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Genome-wide scan for self-rating of the effects of alcohol in American Indians.
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In one study, heritability was found to be 60% for a composite sensitivity measure that was used during an alcohol challenge in twins (Heath et al., 1999). Correlations of level of response to alcohol using body sway and the Subjective High Assessment Scale (SHAS) in an alcohol challenge paradigm using sibling pairs as participants was reported to be 0.36 (Wilhelmsen et al., 2003). Lower correlations were found in first-degree relatives using a retrospective self-report measure to assess level of response to alcohol (0.12–0.22).