Chunk #19 — 2. METHODS — 2.3 Statistical Analyses — Common Pathway model

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Genetic etiology of the common liability to drug dependence: evidence of common and specific mechanisms for DSM-IV dependence symptoms.

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Both multivariate genetic models have the potential to identify shared genetic and environmental mechanisms across alcohol, tobacco and cannabis; however, the Common Pathway model represents a testable hypothesis that there is a single underlying process. Genetic and environmental effects on the latent factor highlight differences in the mechanism that bring about liability to developing dependence symptoms on an array of substances.