= \max _{r \in R} \left[ {{\rm COXSIM_{1\% }^g} (r)} \right] \end{equation*}\end{document}To assess statistical significance, the \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{upgreek} \usepackage{mathrsfs} \setlength{\oddsidemargin}{-69pt} \begin{document} }{}${{\it maxCOXSIM}_{1\% }^g}$\end{document} value is compared with the null distribution generated under the same number of genes in listg. On the COXPRESdb, the significance level, which we call the supportability, is shown as the number of stars according to the following P-value thresholds: 1E-04 for one star, 1E-16 for two stars and 1E-32 for three stars (example: http://coxpresdb.jp/cgi-bin/coex_list.cgi?gene=7535&sp=Hsa). Detail explanation for supportability is shown in the COXPRESdb help page [http://coxpresdb.jp/help/supportability/].
