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Chunk #13 — EVALUATION OF THE QUALITY OF COEXPRESSED GENE LIST — Refinement of the statistical evaluation of each coexpressed gene list

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COXPRESdb in 2015: coexpression database for animal species by DNA-microarray and RNAseq-based expression data with multiple quality assessment systems.
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The numbers of genes at each significance level are summarized in Figure 1. Human, mouse and fly show higher populations of high supportability level genes than the other species, reflecting the fact that these species have multiple platforms that are most suitable to prove the reliability of the coexpressed gene lists. Note that ‘No star’ does not always mean unreliable. ‘No star’ is also available for coexpression specifically observed in the species, or it may just result from the lack of an appropriate reference platform. Even so, for general purposes, a high supportability level of coexpression is recommended to prioritize genes. As the human platforms have strong coexpression support (Figure 1), the human coexpression data in COXPRESdb are one of the most important resources for human research.