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Chunk #23 — WORKING GROUP CONSIDERATIONS — Incidental Findings in Children

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ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.
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of the patient could place an unrealistic burden upon laboratories facing increasing volumes of clinical sequencing. The Working Group also felt that the ethical concerns about providing children with genetic risk information about adult-onset diseases were outweighed by the potential benefit to the future health of the child and the child’s parent of discovering an incidental finding where intervention might be possible. Therefore, the Working Group recommended that recommendations for seeking and reporting incidental findings not be limited by the age of the person being sequenced.