The association schizophrenia liability genes with oscillatory brain activity and the specific tissues with significantly altered expression highlights where oscillatory brain activity changes with increased disease risk. Altered expression of ITIH4 in the frontal cortex in the context of schizophrenia has recently been reported (Ohi et al., 2016), and is consistent with reduced alpha oscillatory activity in the frontal cortex observed in schizophrenia (Iacono, 1982; Itil, Saletu, Davis, & Allen, 1974; Klimesch, Sauseng, & Hanslmayr, 2007; Sponheim et al., 1994; Sponheim, Clementz, Iacono, & Beiser, 2000). FDR significant SNPs were eQTLs for ITIH4, GLN3, and MTERF4 in the frontal cortex for Cz alpha oscillations. Our results indicate that schizophrenia liability gene ITIH4 affects oscillatory brain function and adds GNL3 and MTERF4 as possible target genes. Brain eQTLs further pointed to cytokine receptor genes IL1RL1 and IL18R1, which are immune system genes linked to asthma, celiac disease, IBS, and atopic dermatitis (Barreto‐Luis et al., 2016; Dubois et al., 2010; Liu et al., 2015; Paternoster et al., 2015). MetaXcan imputed expression analysis indicated that these genes are also brain expressed and associated
