Phenotypic analyses of sample 1 showed that the 12 neuroticism items correlated positively with each other (.17–.54, Supplementary Fig. 1), and with the weighted sum-score (‘sum-score’ henceforward; .51–.68, see Methods for information on how the sum-score was constructed). Associations of all 12 items and the sum-score with external (demographic/psychological) variables had largely the same sign, but occasionally showed considerable differences in magnitude (Supplementary Tables 3, 4; Supplementary Figs 2, 3).