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Chunk #5 — Introduction

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The impact of focusing a program to prevent heavier drinking on a pre-existing phenotype, the low level of response to alcohol.
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In 2012, our group published a pilot study of 64 freshman to evaluate whether an Internet-based personalized prevention approach that focused on a Low LR to alcohol was effective. We created two sets of four videos, with one set based on the low LR to alcohol (a Low LR-Based [LRB] Group) and the other incorporating more generic State of the Art (SOTA) information without an emphasis on any model of risk. We then compared drinking outcomes over eight weeks in drinking college freshmen (Schuckit et al., 2012a). Similar to procedures described in the Methods below, both LRB and SOTA videos used didactic presentations that incorporated key elements of Motivational Interviewing (MI) and Brief Intervention (BI). Video sets for the two groups differed in that all examples in LRB videos were based on the model of how the impact of a Low LR on heavier drinking operated partly through environmental mediators (e.g., selecting heavier drinking friends) and attitudes (e.g., positive alcohol expectancies) (Schuckit et al., 2011a, 2011b), while examples in SOTA videos focused on negative affect and impulsivity as risk factors