One practical aspect of utilizing continental AIMs is to identify sets of individuals corresponding to a particular continental group. The ability of In4 sets to exclude subjects from the different self identified groups is summarized in Table 3 using the predominant population group cluster membership as the standard for each continent. Two criteria, 10% non-membership and 15% non-membership are shown. In general, the 128 In4 AIMs and smaller sets showed nearly complete exclusion of individuals with other self-identified ancestries when considering any of the continental groups. However, for European, there was a large decrease in the performance of smaller maker sets (<64 markers) with respect to exclusion of South Asian subjects.
