To benchmark our sample with epidemiological studies, we looked at items in the National Survey on Drug Use and Health (NSDUH), a population-based epidemiological survey on substance use 29. Because the controls used for this dataset were drawn almost exclusively from the Los Angeles area, we restricted the surveyed data to subjects age 20-55 from California. We used the following items, directly corresponding to the substance use measurements in the GPC: During the past 30 days ... on how many days did you have 5 or more drinks on the same occasion (DR5DAY)? [an answer of > 3 (weekly or more) was used to correspond to GPC item 1]Have you smoked 100 cigarettes in your entire life (CIG100LF)?Has there ever been a period in your life when you smoked cigarettes every day for at least 30 days (CIGDLYMO)?Total # of days used marijuana in the past 12 months (MJYRTOT). [an answer of > 0 was used to correspond to GPC item 4]Illicit drug use (except marijuana), past year (IEMYR).