The hallmarks are freely available as the H Collection in the MSigDB v5.0 and can be used by any enrichment analysis method that relies on gene sets. The name of every gene set in this collection starts with HALLMARK to distinguish them from other MSigDB gene sets. Table 1 lists all 50 hallmarks by their names and provides their biological process category, a brief description and additional statistics such as their size and their number of founder gene sets. Table S3 contains detailed statistics for the gene sets used to make the hallmarks and their cluster assignments. Each hallmark set and all of its annotations appear on a separate web page of the MSigDB web site (see example in Figure S2). This page also provides a brief description of each hallmark and follows the standard conventions for MSigDB gene sets. In addition every hallmark page contains links to its founder gene sets and includes details about specific datasets and phenotype class comparisons that were used to refine and validate the hallmark. This information is particularly useful when interpreting enrichment analysis
