for more than 9 months. Among never users of antidepressants, there were 40 suicides, nine among never smokers, seven among former smokers, and 24 among active smokers (in 1975); among them, the risk of suicide was 2.50 (95% CI 1.15–5.42) for active smokers. If we further excluded those with antipsychotic use or disability pension for psychiatric illness, the HR for active smokers among those who received no prescriptions for antidepressant medication was 3.26 (95% CI 1.32–8.08). Further adjustment for pre-existing depressiveness (LSS score) in 1975, binge alcohol use in 1975, or sedative–hypnotic medication use did not significantly change the risk (HR 3.12, 95% CI 1.20–8.13).