Of the 410 genes, 353 were uniquely mapped to the GO database. The unmapped genes were non-coding RNAs, anti-sense RNAs, pseudo-genes, and read-throughs. Fifty-four GOBPs had false discovery rate (FDR) P-values < 0.05, including ethanol oxidation, synaptic signaling, synapse organization, synaptic plasticity, startle response, neurogenesis, nervous system development, learning or memory, protein metabolic process, cell adhesion, cell development, cell junction organization, movement of cell or subcellular component, cell-cell signaling, regulation of signaling, etc. (Table S5). Three hundred and seventy-four genes were mapped to GTEx V8 DEG sets and enrichment results are in Fig. S2. The majority of the enrichment sets were found in brain tissues but also included liver, kidney, and other tissues as well (Fig. S2).
