cerebral processes of inhibitory control; however, it remains unclear whether impaired inhibitory control predisposes individuals to problem drinking or results from drinking problems. To address this issue would again require longitudinal studies of both at-risk and control populations prior to the start of alcohol use, affected individuals and their non-affected siblings, as well as individuals with and without family history of alcoholism. Finally, although the participants all denied current use of illicit substance and showed negative urine screens at time of fMRI, we did not evaluate their history of illicit substance use, which may influence the current findings.
