cannot be fully characterized by behavioral tasks that solely address motor response inhibition. Thus, paradigms that examine delay discounting, risky decision making, reward responsivity would need to be considered to understand the multifaceted etiologies of alcohol misuse (Moreno et al., 2012; Rossiter et al., 2012). Fourth, the SST is widely used to probe cognitive control, but the SSRT as a measure of inhibitory control appears to be noisy and not as robust when compared to the neural responses to inhibitory control. A more sophisticated approach is to estimate the distribution of SSRT, which requires a much greater number of stop trials than available from the current study. Fifth, some investigators consider AlphaSim as a liberal threshold. Thus, many of the clusters we identified here survived a corrected cluster threshold; these findings need to be replicated and confirmed in additional work. Sixth, the current results distinguish the influence of problems associated with alcohol use from the duration of drinking on the cerebral processes of inhibitory control; however, it remains unclear whether impaired inhibitory control predisposes individuals to problem drinking or results from drinking problems. To address this issue would again require longitudinal studies of both at-risk and control populations prior to
