The second interesting result from Table 2 is that in AAs, there is nominal evidence for association at multiple SNPs in CHRNA7. For CHRNA7, the most significant SNP in the AAs is rs6494212 (OR = 1.44 (1.14-1.83), p = 0.0027), but in all the EAs, OR = 1.1 (0.96-1.26) and p = 0.16. However, rs904951 shows some consistent evidence in both populations (OR = 1.30 (1.02-1.65), p = 0.03 in AAs and OR = 1.12 (0.99-1.27), p = 0.069 in EAs). Other CHRNA7 SNPs such as rs4779565 and rs10438287 have p < 0.05 in EAs and consistent odds ratios in both populations (Supplementary Table 2).
