connections (141 edges) and these linked brain regions that were more widely separated, including connections between the frontopolar or DLPFC and the temporal or parietooccipital regions bilaterally (Figure 3C). The beta band also contained a large number of significantly different connections (121 edges) that formed a dense network within the frontal and temporal regions, both within and across hemispheres. There were fewer differences in long distance connections between the prefrontal and posterior regions in this band compared with lower frequency bands (Figure 3D). Further detail on the differences in connection strength CE between MDD and control subjects, with results for each edge in each frequency band, are shown in Table S1. This Table S1 reports details of Student's-t and Kruskal Wallis tests, associated p-values, and q-values. For all significant edges, the mean coherence values were higher in the MDD than in the control group.